Buy Genuine Original/Generic DESCOVY in Bangkok, Phuket, Pattaya, Chiang Mai, Koh Samui, Thailand
Buy Genuine Original or Generic DESCOVY in Bangkok, Phuket, Pattaya, Chiang Mai, Koh Samui, Thailand
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What is PrEP?
PrEP (Pre-Exposure Prophylaxis) is an HIV prevention method that involves taking antiviral medication before potential exposure to HIV. It is designed for individuals at high risk of infection. Unlike HIV treatment, PrEP helps prevent the virus from establishing an infection.
When taken consistently as prescribed, PrEP can reduce the risk of HIV infection by up to 90%. It is particularly beneficial for individuals engaging in high-risk sexual behaviors, including those with multiple partners, partners with unknown HIV status, sex workers, and those in serodiscordant relationships.
DESCOVY for PrEP
DESCOVY for PrEP is a daily prescription medication designed for adults and adolescents at risk of contracting HIV. It significantly reduces the likelihood of HIV transmission through sexual activity.
Emtricitabine/Tenofovir Alafenamide (FTC/TAF)
Descovy is a newer PrEP medication containing emtricitabine and tenofovir alafenamide (TAF) instead of tenofovir disoproxil fumarate (TDF). F/TAF delivers higher concentrations of tenofovir into cells, reaches protective levels faster, and sustains those levels longer than F/TDF. These attributes may make F/TAF more effective for individuals who occasionally miss doses.
In the DISCOVER study, F/TAF was found to be "non-inferior" to F/TDF for PrEP, meaning it was equally effective. The study reported more HIV infections among participants using F/TDF (11 cases) compared to those using F/TAF (6 cases), excluding individuals with suspected acute HIV infections at baseline. Although this difference was not statistically significant, the findings confirm that F/TAF is a reliable option for PrEP.
What are Truvada & Descovy?
Truvada: Truvada was one of the first medications approved for PrEP. It contains emtricitabine and tenofovir disoproxil fumarate (F/TDF). When taken daily, Truvada is highly effective in preventing HIV transmission and is approved for all individuals at risk, including those assigned female at birth.
Descovy: Descovy is a newer PrEP option containing emtricitabine and tenofovir alafenamide (F/TAF). Compared to Truvada, Descovy delivers higher concentrations of tenofovir into cells and sustains protective levels longer, making it potentially more effective for those who occasionally miss doses.
Comparison: Truvada vs. Descovy
| Category | Truvada | Descovy |
|---|---|---|
| FDA Approval | August 2, 2004 | April 4, 2016 |
| Approved for PrEP | 2012 | October 3, 2019 |
| Generic Name | Emtricitabine 200mg + Tenofovir disoproxil fumarate (TDF) 300mg | Emtricitabine 200mg + Tenofovir alafenamide (TAF) 25mg |
| Indications for PrEP | At-risk adults and adolescents (≥35 kg) | At-risk adult and adolescent men & transgender women (≥35 kg) |
| Indications for Treatment | HIV-1 infection (≥17 kg) | HIV-1 infection (≥25 kg) |
| Pill Size | Larger | Smaller |
| Kidney Impact | May cause kidney issues in ~3% of users | Lower impact on kidney function |
| Best For | Younger users with good kidney function | Older users or those with kidney concerns |
| Recommended for Daily Use? | Yes | Yes |
| Recommended for On-Demand PrEP (2-1-1)? | Yes | No (limited studies) |
| Recommended for Anal Sex? | Yes | Yes |
| Recommended for Vaginal Sex? | Yes | No |
| Cost in USA | $30–$250 per bottle (30 tabs) | $712–$720 per bottle (30 tabs) |
| Cost in Thailand | $90 per bottle (30 tabs) | Generic versions only |
| Cost of Generics in USA | $100 per bottle (30 tabs) | $100 per bottle (30 tabs) |
How Does PrEP Reduce the Risk of HIV Infection?
PrEP works by preventing the HIV virus from replicating in the body. When taken consistently, the medication binds to immune cells in the blood and genital tissues, blocking the pathways HIV typically uses to establish an infection.
While PrEP significantly reduces the risk of HIV transmission, it is not a cure. For maximum protection, it must be taken daily as prescribed. Since PrEP does not protect against other STIs, it is recommended to use condoms alongside PrEP for comprehensive protection.
Precautions with PrEP
- PrEP is not a treatment for HIV. If you suspect recent exposure to HIV, get tested immediately.
- Some mild side effects, such as nausea or headaches, may occur but usually subside after a few days.
- PrEP must be prescribed by a healthcare provider who will determine if it is suitable for you.
PrEP Pricing at PULSE Clinic Koh Samui
PULSE Clinic at Koh Samui offers fast delivery of HIV PrEP with worldwide shipping, ensuring accessibility no matter where you are!
Who Should Take PrEP?
PrEP is recommended for individuals at high risk of HIV infection, including:
- People with multiple sexual partners or those with partners of unknown HIV status.
- Individuals engaging in high-risk behaviors, such as unprotected sex or needle sharing.
- Serodiscordant couples (one partner is HIV-positive, the other is HIV-negative).
- Those who have frequently used PEP (post-exposure prophylaxis) and struggle to reduce risky behaviors.
A consultation with a healthcare provider can help determine if PrEP is right for you. Regular follow-ups are necessary to monitor its effectiveness and manage potential side effects.
How to take PrEP
PrEP can be taken in 2 ways:
- On-Demand PrEP: Take the medication 2-24 hours before a high-risk activity, followed by a dose within 24 hours, and another dose 24 hours after the second. This method is for people who have intermittent risks.
- Daily PrEP: Take one pill every day at the same time to maintain consistent levels of medication in the body, ensuring continuous protection. Daily PrEP is generally recommended for its convenience and higher effectiveness.
Steps for Daily Dosing
- Get a prescription from a healthcare provider.
- Take one pill daily, at the same time, with or without food.
- Schedule check-ups every 3 months.
- Use PrEP alongside condoms for the best protection.
- Keep a consistent supply of medication.
- Report any unusual side effects to your healthcare provider.
The Importance of PrEP in HIV Prevention
PrEP plays a crucial role in HIV prevention, especially in high-risk regions like Chiang Mai, where both locals and tourists benefit from increased awareness. By providing accurate and clear information on PrEP’s safety and effectiveness, individuals can make informed decisions to protect themselves and their communities.
Nootsara B.
