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Top HIV Medications Compared: Uses, Side Effects & Generic Equivalents

11 Apr 2025

HIV Drug Chart: What Each Medication Does & Common Side Effects

Choosing the right HIV medication can feel overwhelming with so many options available. This guide provides a side-by-side comparison of commonly prescribed HIV drugs — including brand names, generic equivalents, their benefits, and potential side effects — to help patients and caregivers make informed decisions in consultation with healthcare providers.

Brand Name 

(Generic Name)

Pros

Common Side Effects

Tivicay 

(Dolutegravir)

High barrier to resistance, once-daily dosing, potent viral suppressionInsomnia, headache, diarrhea, nausea, fatigue, rash

Viramune 

(Nevirapine)

Effective in lowering viral load, available in generic formSkin rash, fever, nausea, vomiting, liver issues

Taficita 

(Emtricitabine + Tenofovir Alafenamide)

Lower kidney and bone toxicity, once-daily doseDiarrhea, nausea, headache, dizziness, fatigue, rash

Teno-EM 

(Emtricitabine + Tenofovir Disoproxil)

Widely used, effective for both treatment and PrEP, available as genericNausea, diarrhea, dizziness, insomnia, abnormal dreams, skin discoloration

Tavin-EM 

(Emtricitabine + Tenofovir Disoproxil)

Affordable, accessible, used globallyNausea, fatigue, headache, rash, insomnia

Tenof-EM 

(Emtricitabine + Tenofovir Disoproxil)

Same benefits as Truvada, often cheaperHeadache, nausea, dizziness, skin issues

Ricovir-EM 

(Emtricitabine + Tenofovir Disoproxil)

Effective for HIV and PrEP, widely availableNausea, fatigue, diarrhea, abnormal dreams

Tenof EM 

(Emtricitabine + Tenofovir Disoproxil)

Good tolerability, commonly used in public health programsDizziness, insomnia, skin discoloration

TEEVIR 

(Emtricitabine + Tenofovir Disoproxil)

Combination pill improves adherenceFatigue, nausea, rash

Truvada 

(Emtricitabine + Tenofovir Disoproxil)

Strong evidence for PrEP and treatment, trusted global brandNausea, diarrhea, headache, skin rash

Edurant 

(Rilpivirine)

Once-daily dosing, fewer CNS effects than alternativesDepression, insomnia, headache, nausea, rash

Tenofovir 

(Tenofovir Disoproxil Fumarate)

Key component in many regimens, used for HIV and Hep BKidney and bone issues, nausea, fatigue, diarrhea

ATRIPLA 

(Efavirenz + Emtricitabine + Tenofovir)

Single-tablet regimen, simplifies treatmentDizziness, depression, rash, insomnia, liver/kidney issues

 

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